With approximately 30+ million of Americans suffering from arthritic and degenerative conditions, scientists and other researchers have found a new biological treatment in the field of regenerative medicine known as

Alpha 2 Macroglobulin (A2M).

What is A2M?

Osteoarthritis (OA) is due to the diseased joint overproducing proteases and cytokines that are trapped in the joint. Because they are trapped, they lead to chronic pain and cartilage damage. Inhibiting these cytokines and proteases with A2M can stop the progression of OA by preventing cartilage break down. This combination may lead to a reversal of joint degeneration and pain that was not available before.

A2M is naturally occurring, but unable to enter the joints in adults in large enough quantities because of its large size and the avascular structure or these tissues.

A2M is a plasma protein and is found in significant quantities in the blood. When concentrated and injected into an arthritic joint, A2M is able to inactivate a variety of cytokines and proteases that are known to cause degradation of cartilage and pain.

Scientific evidence points to A2M as the key to stopping osteoarthritis and pain at the molecular level.

Who is a Good Candidate for A2M?

• Osteoarthritis (Knee arthritis, Hip arthritis)

• Joint injuries (Shoulder, Knee, Elbow, Rotator cuff)

• Labral Tear

• Torn meniscus

• Spinal injuries (Neck, Back)

• Lumbar and sacral osteoarthritis

• Sciatica (Lumbar radiculopathy)

• Herniated disc (Slipped disc, Disc displacement)

• Degenerative disc disease

• Neuropathy

How does A2M Therapy Work?

• At your appointment, your blood will be drawn and spun in a centrifuge to separate and concentrate the A2M.

• The A2M will then be injected into your joint.

• The procedure is minimally-invasive, and not painful.

• Most patients tell us they feel an improvement in symptoms and mobility the very same day.

• Early, regular treatments may relieve pain, promote tissue growth, and slow or stop the progression of joint degeneration.

• It may even prevent or limit the onset of post-traumatic osteoarthritis.

Where Can I get A2m Therapy?

You can get A2M Therapy right here at MIMI's! Dr Paula Marchionda is well trained in the therapy and enjoys helping folks maintain their joint health naturally.

Want to learn more? Call us to schedule a new patient appointment and explore your options.